Former and Current PhD Students

(7) Ms. Annisa Indah Reza (Indonesian SSP Student) Apr. 2021-


Recent Advances in Synthesis of Multiply Arylated/Alkylated Pyridines
Annisa Indah Reza, Kento Iwai, Nagatoshi Nishiwaki
The Chemical Record 2022, 22, e202200099 (20 pages). (DOI: 10.1002/tcr.202200099)




(6) Dr. Yusuke Mizuta (Japanese PhD Course Student with working at YAMAKIN CO., LTD.) Oct. 2019-Sep. 2022


Graft Polymerization of Methyl Methacrylate on the Surface of Poly(ethylene-co-tetrafluoroethylene) using Benzoyl Peroxide as Initiator
Yusuke Mizuta, Ryuichi Sugimoto, Hiromu Okada, Chao Zhao, Kazuya Kobiro, Nagatoshi Nishiwaki
Journal of Applied Polymer Science 2022, e52415 (8pages). (DOI: 10.1002/app.52415)




Surface Functionalization of Ethylene–Tetrafluoroethylene Copolymer Film with Poly(Methyl Methacrylate) via Chemical Radical Polymerization
Yusuke Mizuta, Hiromu Okada, Chao Zhao, Ryuichi Sugimoto, Nagatoshi Nishiwaki, Kazuya Kobiro
Polymer 2021, in press. (DOI: 10.1016/j.polymer.2021.123826 )


(5) Dr. Masato Ohsumi (Japanese Special PhD Course Student with working at Kochi National College of Technology) Oct. 2017-Sep. 2018

Substrate Switchable Suzuki-Miyaura Coupling for Benzyl Ester vs. Benzyl Halide
Masato Ohsumi, Akitaka Ito, and Nagatoshi Nishiwaki
RSC Advances 2018, 8, 35056-35061. (DOI: 10.1039/c8ra07841f)




Selective Synthesis of (Benzyl)biphenyls by Successive Suzuki-Miyaura Coupling of Phenylboronic Acids with 4-Bromobenzyl Acetate under Air Atmosphere
Masato Ohsumi and Nagatoshi Nishiwaki
ACS Omega 2017, 2, 7767-7771. (DOI: 10.1021/acsomega.7b01450)



(4) Dr. Feiyue Hao (Chinese SSP Student) Apr. 2015-Mar. 2018 then Taizhou University (China)

Intramolecular Arylation of 2-Bromobenzenesulfonamides Using DMSO/HCOONa·2H2O System: Efficient Access To Dibenzosultams
Feiyue Hao, Guyue Liu, Zhengneng Jin, Guoliang Dai, Wubing Yao, Nagatoshi Nishiwaki, Jiashou Wu
Advanced Synthesis & Catalysis 2022, 364, 1889-1895. (DOI: 10.1002/adsc.202200140)




A Mechanistic Study for Aziridination of Nitroalkenes Mediated by N-Chlorosuccinimide
Kento Iwai, Khimiya Wada, Feiyue Hao, Haruyasu Asahara, Nagatoshi Nishiwaki
Journal of Oleo Science 2022, 71, 897-903. (DOI: 10.5650/jos.ess21406)




Recent Progress in Nitro-promoted Direct Functionalization of Pyridones and Quinolones
Feiyue Hao and Nagatoshi Nishiwaki
Molecules 2020, 25, 673 (24 pages). (DOI: 10.3390/molecules25030673)



Chemistry of Nitroaziridines
Feiyue Hao and Nagatoshi Nishiwaki
Heterocycles 2019, 99, 54-72. (DOI: 10.3987/REV-18-SR(F)2)




Direct Dihalo-Alkoxylation of Nitroalkenes Leading to β,β-Dihalo-β-nitroethyl Alkyl Ethers
Feiyue Hao, Soichi Yokoyama and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2018, 16, 2768-2775. (DOI: 10.1039/C8OB00408K)



Direct Aziridination of Nitroalkenes Affording N-Alkyl-C-nitroaziridines and the Subsequent Lewis Acid Mediated Isomerization to β-Nitroenamines
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic Letters 2017, 19, 5442-5445. (DOI: 10.1021/acs.orglett.7b02724)



Direct Amino-halogenation and Aziridination of the 2-Quinolone Framework by Sequential Treatment of 3-Nitro-2-quinolone with Amine and N-Halosuccinimide
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron 2017, 73, 1255-1264. (DOI: DOI:/10.1016/j.tet.2017.01.028)
Selected as a front cover of the issue.



A Direct and Vicinal Functionalization of the 1-Methyl-2-quinolone Framework: 4-Alkoxylation and 3-Chlorination
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2016, 14, 5128-5135. (DOI: 10.139/C6OB00868B)



Direct and Efficient Functionalization of the 1-Methyl-2-quinolone Framework
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Procedia Engineering 2017, 174, 1058-1066. (DOI: DOI:10.1016/j.proeng.2017.01.258)



(3) Dr. Sho Hirai (Japanese SSP Student) Apr. 2014-Mar. 2017 then Fukuoka University (Japan)

Tailor-made Synthesis of Fully Alkylated/Arylated Nicotinates by FeCl3-Mediated Condensation of Enamino Esters with Enones
Sho Hirai, Yurie Horikawa, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemical Communications 2017, 53, 2390-2393. (DOI: DOI:/10.1039/C7CC00051K)



Acid Promoted Dimerization of α-Amino-α,β-unsaturated Amides Affording Bis(functionalized) Pyrrolinones
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron Letters 2016, 57, 5896-5898. (DOI: 10.1016/j.tetlet.2016.11.068)



Chemoselective Amination of β-Keto Amides
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Current Organic Chemistry 2016, 20, 2911-2916. (DOI: 10.2174/1385272820666160608101354)



Revisiting Dimerization of Acetoacetamide Leading to 4,6-Dimethyl-2-pyridone-5-carboxamide
Sho Hirai, Haruyasu Asahara, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Journal of Oleo Science 2014, 63, 939-942.



An NMR Study on a Pseudo-Intramolecular Transacylation Reaction of an α-Aryl-β-keto Ester
Sho Hirai, Haruyasu Asahara, Shotaro Hirao, Jun Sawayama, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
RSC Advances 2014, 4, 4889-4892.



(2) Dr. Song Thi Le (Vietnamien SSP Student) Apr. 2012-Sep. 2014 (Early Graduation), and now working at Vietnam Institute for Building Materials (Vietnam)

Three-Component Ring Transformations
Nagatoshi Nishiwaki, Song Thi Le and Haruyasu Asahara
Encyclopedia , 8692.


Synthesis of Nitroaromatic Compounds via Three-Component Ring Transformations
Song Thi Le, Haruyasu Asahara and Nagatoshi Nishiwaki
Molecules 2021, 26, 639 (18 pages). (DOI: 10.3390/ molecules26030639 )
For special issue "25th Anniversary of Molecules—Recent Advances in Organic Synthesis "




Synthesis of 6-Substituted 2-Phenacylpyridines from 2-(Phenylethynyl)pyridine via Isoxazolo[2,3-a]pyridinium Salt
Song Thi Le, Toshiki Fujimoto, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2016, 14, 10674-10682. (DOI: 10.139/C6OB01942K)



Dual Behavior of Iodine Species in Condensation of Anilines and Vinyl Ethers Affording 2-Methylquinolines
Song Thi Le, Chisa Yasuoka, Haruyasu Asahara, and Nagatoshi Nishiwaki
Molecules 2016, 21, 827 (11 pages). (DOI: 10.3390/molecules21070827)



Synthesis of Nitroarenes Using Three-Component Ring Transformation
Haruyasu Asahara, Song The Le, and Nagatoshi Nishiwaki
Journal of Synthetic Organic Chemistry, Japan 2016, 74, 130-140. (Invited) (DOI: 10.5059/yukigoseikyokaishi.74.130)




An Alternative Synthetic Approach to 3-Alkylated/Arylated 5-Nitropyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 2015, 80, 8856-8858.



Metal-free Synthesis of 2-Alkenyl/Alkynyl-5-nitropyridines Using a Three-component Ring Transformation
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemistry Letters 2015, 44, 776-778.



Tailor-made Synthesis of N,N,2,6-Tetrasubstituted 4-Nitroanilines by Three-Component Ring Transformation of Dinitropyridone
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2015, 1203-1206.



An Efficient Synthesis of Nitrated Cycloalka[b]pyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Synthesis 2014, 46, 2175-2178.



Synthesis of 2-Aryl-5-Nitropyridines by Three-Component Ring Transformation of 3,5-Dinitro-2-pyridone
Song Thi Le, Haruyasu Asahara, Kazuya Kobiro, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Asian Journal of Organic Chemistry 2014, 3, 297-302.



(1) Dr. Xin Chen (Chinese SSP Student) Oct. 2010-Sep.2013 then Hubei Pharmaceutical University (China)

Reactive 2-Quinolones Dearomatized by Steric Repulsion between 1-Methyl and 8-Substituted Groups
Xin Chen, Kazuya Kobiro, Haruyasu Asahara, Kiyomi Kakiuchi, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Tetrahedron 2013, 69, 4624-4630.



One-step and Non-catalytic Intramolecular Redox reactions of Conjugated All E-Dienals to Non-conjugated Z-Enoic Acids in Subcritical Water
Xin Chen, Kana Sumoto, Tetsuya Yamagami, Kazuya Yokoyama, Pengyu Wang, Shotaro Hirao, Nagatoshi Nishiwaki, and Kazuya Kobiro
The Journal of Supercritical Fluids 2012, 62, 178-183.