Former and Current PhD Students

(7) Ms. Annisa Indah Reza (Indonesian SSP Student) Apr. 2021-


Recent Advances in Synthesis of Multiply Arylated/Alkylated Pyridines
Annisa Indah Reza, Kento Iwai, Nagatoshi Nishiwaki
The Chemical Record 2022, 22, e202200099 (20 pages). (DOI: 10.1002/tcr.202200099)




(6) Dr. Yusuke Mizuta (Japanese PhD Course Student with working at YAMAKIN CO., LTD.) Oct. 2019-Sep. 2022


Graft Polymerization of Methyl Methacrylate on the Surface of Poly(ethylene-co-tetrafluoroethylene) using Benzoyl Peroxide as Initiator
Yusuke Mizuta, Ryuichi Sugimoto, Hiromu Okada, Chao Zhao, Kazuya Kobiro, Nagatoshi Nishiwaki
Journal of Applied Polymer Science 2022, e52415 (8pages). (DOI: 10.1002/app.52415)




Surface Functionalization of Ethylene–Tetrafluoroethylene Copolymer Film with Poly(Methyl Methacrylate) via Chemical Radical Polymerization
Yusuke Mizuta, Hiromu Okada, Chao Zhao, Ryuichi Sugimoto, Nagatoshi Nishiwaki, Kazuya Kobiro
Polymer 2021, in press. (DOI: 10.1016/j.polymer.2021.123826 )


(5) Dr. Masato Ohsumi (Japanese Special PhD Course Student with working at Kochi National College of Technology) Oct. 2017-Sep. 2018


Substrate Switchable Suzuki-Miyaura Coupling for Benzyl Ester vs. Benzyl Halide
Masato Ohsumi, Akitaka Ito, and Nagatoshi Nishiwaki
RSC Advances 2018, 8, 35056-35061. (DOI: 10.1039/c8ra07841f)




Selective Synthesis of (Benzyl)biphenyls by Successive Suzuki-Miyaura Coupling of Phenylboronic Acids with 4-Bromobenzyl Acetate under Air Atmosphere
Masato Ohsumi and Nagatoshi Nishiwaki
ACS Omega 2017, 2, 7767-7771. (DOI: 10.1021/acsomega.7b01450)



(4) Dr. Feiyue Hao (Chinese SSP Student) Apr. 2015-Mar. 2018 then Taizhou University (China)

Intramolecular Arylation of 2-Bromobenzenesulfonamides Using DMSO/HCOONa·2H2O System: Efficient Access To Dibenzosultams
Feiyue Hao, Guyue Liu, Zhengneng Jin, Guoliang Dai, Wubing Yao, Nagatoshi Nishiwaki, Jiashou Wu
Advanced Synthesis & Catalysis 2022, 364, 1889-1895. (DOI: 10.1002/adsc.202200140)




A Mechanistic Study for Aziridination of Nitroalkenes Mediated by N-Chlorosuccinimide
Kento Iwai, Khimiya Wada, Feiyue Hao, Haruyasu Asahara, Nagatoshi Nishiwaki
Journal of Oleo Science 2022, 71, 897-903. (DOI: 10.5650/jos.ess21406)




Recent Progress in Nitro-promoted Direct Functionalization of Pyridones and Quinolones
Feiyue Hao and Nagatoshi Nishiwaki
Molecules 2020, 25, 673 (24 pages). (DOI: 10.3390/molecules25030673)



Chemistry of Nitroaziridines
Feiyue Hao and Nagatoshi Nishiwaki
Heterocycles 2019, 99, 54-72. (DOI: 10.3987/REV-18-SR(F)2)




Direct Dihalo-Alkoxylation of Nitroalkenes Leading to β,β-Dihalo-β-nitroethyl Alkyl Ethers
Feiyue Hao, Soichi Yokoyama and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2018, 16, 2768-2775. (DOI: 10.1039/C8OB00408K)



Direct Aziridination of Nitroalkenes Affording N-Alkyl-C-nitroaziridines and the Subsequent Lewis Acid Mediated Isomerization to β-Nitroenamines
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic Letters 2017, 19, 5442-5445. (DOI: 10.1021/acs.orglett.7b02724)



Direct Amino-halogenation and Aziridination of the 2-Quinolone Framework by Sequential Treatment of 3-Nitro-2-quinolone with Amine and N-Halosuccinimide
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron 2017, 73, 1255-1264. (DOI: DOI:/10.1016/j.tet.2017.01.028)
Selected as a front cover of the issue.



A Direct and Vicinal Functionalization of the 1-Methyl-2-quinolone Framework: 4-Alkoxylation and 3-Chlorination
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2016, 14, 5128-5135. (DOI: 10.139/C6OB00868B)



Direct and Efficient Functionalization of the 1-Methyl-2-quinolone Framework
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Procedia Engineering 2017, 174, 1058-1066. (DOI: DOI:10.1016/j.proeng.2017.01.258)



(3) Dr. Sho Hirai (Japanese SSP Student) Apr. 2014-Mar. 2017 then Fukuoka University (Japan)


Tailor-made Synthesis of Fully Alkylated/Arylated Nicotinates by FeCl3-Mediated Condensation of Enamino Esters with Enones
Sho Hirai, Yurie Horikawa, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemical Communications 2017, 53, 2390-2393. (DOI: DOI:/10.1039/C7CC00051K)



Acid Promoted Dimerization of α-Amino-α,β-unsaturated Amides Affording Bis(functionalized) Pyrrolinones
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron Letters 2016, 57, 5896-5898. (DOI: 10.1016/j.tetlet.2016.11.068)



Chemoselective Amination of β-Keto Amides
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Current Organic Chemistry 2016, 20, 2911-2916. (DOI: 10.2174/1385272820666160608101354)



Revisiting Dimerization of Acetoacetamide Leading to 4,6-Dimethyl-2-pyridone-5-carboxamide
Sho Hirai, Haruyasu Asahara, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Journal of Oleo Science 2014, 63, 939-942.



An NMR Study on a Pseudo-Intramolecular Transacylation Reaction of an α-Aryl-β-keto Ester
Sho Hirai, Haruyasu Asahara, Shotaro Hirao, Jun Sawayama, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
RSC Advances 2014, 4, 4889-4892.



(2) Dr. Song Thi Le (Vietnamien SSP Student) Apr. 2012-Sep. 2014 (Early Graduation), and now working at Vietnam Institute for Building Materials (Vietnam)


Assessment of Water Quality under Real-World Conditions: Effects of Steel Slag Backfills on Ground and Surface Water
Song Thi Le, Anh Tuan Le, Mai Thi Tu Cao, Hai Bang Pharm, Tam Thi Nguyen, Thanh Trung Le, Nagatoshi Nishiwaki
Environmental Science: Water Research & Technology 2022, 8, 3043-3053. (DOI: 10.1039/D2EW00649A)




Three-Component Ring Transformations
Nagatoshi Nishiwaki, Song Thi Le and Haruyasu Asahara
Encyclopedia , 8692.


Synthesis of Nitroaromatic Compounds via Three-Component Ring Transformations
Song Thi Le, Haruyasu Asahara and Nagatoshi Nishiwaki
Molecules 2021, 26, 639 (18 pages). (DOI: 10.3390/ molecules26030639 )
For special issue "25th Anniversary of Molecules—Recent Advances in Organic Synthesis "




Synthesis of 6-Substituted 2-Phenacylpyridines from 2-(Phenylethynyl)pyridine via Isoxazolo[2,3-a]pyridinium Salt
Song Thi Le, Toshiki Fujimoto, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2016, 14, 10674-10682. (DOI: 10.139/C6OB01942K)



Dual Behavior of Iodine Species in Condensation of Anilines and Vinyl Ethers Affording 2-Methylquinolines
Song Thi Le, Chisa Yasuoka, Haruyasu Asahara, and Nagatoshi Nishiwaki
Molecules 2016, 21, 827 (11 pages). (DOI: 10.3390/molecules21070827)



Synthesis of Nitroarenes Using Three-Component Ring Transformation
Haruyasu Asahara, Song The Le, and Nagatoshi Nishiwaki
Journal of Synthetic Organic Chemistry, Japan 2016, 74, 130-140. (Invited) (DOI: 10.5059/yukigoseikyokaishi.74.130)




An Alternative Synthetic Approach to 3-Alkylated/Arylated 5-Nitropyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 2015, 80, 8856-8858.



Metal-free Synthesis of 2-Alkenyl/Alkynyl-5-nitropyridines Using a Three-component Ring Transformation
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemistry Letters 2015, 44, 776-778.



Tailor-made Synthesis of N,N,2,6-Tetrasubstituted 4-Nitroanilines by Three-Component Ring Transformation of Dinitropyridone
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2015, 1203-1206.



An Efficient Synthesis of Nitrated Cycloalka[b]pyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Synthesis 2014, 46, 2175-2178.



Synthesis of 2-Aryl-5-Nitropyridines by Three-Component Ring Transformation of 3,5-Dinitro-2-pyridone
Song Thi Le, Haruyasu Asahara, Kazuya Kobiro, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Asian Journal of Organic Chemistry 2014, 3, 297-302.



(1) Dr. Xin Chen (Chinese SSP Student) Oct. 2010-Sep.2013 then Hubei Pharmaceutical University (China)


Reactive 2-Quinolones Dearomatized by Steric Repulsion between 1-Methyl and 8-Substituted Groups
Xin Chen, Kazuya Kobiro, Haruyasu Asahara, Kiyomi Kakiuchi, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Tetrahedron 2013, 69, 4624-4630.



One-step and Non-catalytic Intramolecular Redox reactions of Conjugated All E-Dienals to Non-conjugated Z-Enoic Acids in Subcritical Water
Xin Chen, Kana Sumoto, Tetsuya Yamagami, Kazuya Yokoyama, Pengyu Wang, Shotaro Hirao, Nagatoshi Nishiwaki, and Kazuya Kobiro
The Journal of Supercritical Fluids 2012, 62, 178-183.