2013-2016
2-Azafluorenone Derivatives: Photocatalyst for Oxygenation of Toluene via Electron Transfer and Hydrogen-Atom Transfer
Haruyasu Asahara, Yurie Horikawa, Kento Iwai, Nagatoshi Nishiwaki, Kei Ohkubo
Journal of Photohemistry and Photobiology 2023, 15, 100184 (7pages). (DOI: 10.1016/j.jpap.2023.100184)
A New Approach to 10-Arylated 5H-Dibenzo[b,f]azepines Using syn-Selective Hydrohalogenation of Ethynylaniline
Kento Iwai, Yusuke Mukaijo, Haruyasu Asahara, Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2022, 20, 5543-5550. (DOI: 10.1039/d2ob00950a)
A Mechanistic Study for Aziridination of Nitroalkenes Mediated by N-Chlorosuccinimide
Kento Iwai, Khimiya Wada, Feiyue Hao, Haruyasu Asahara, Nagatoshi Nishiwaki
Journal of Oleo Science 2022, 71, 897-903. (DOI: 10.5650/jos.ess21406)
Development of Synthetic Equivalent of α,α-Dicationic Acetic Acid Leading to Unnatural Amino Acid Derivatives via Tetrafunctionalized Methanes
Haruyasu Asahara, Atsushi Bonkohara, Masaya Takagi, Kento Iwai, Akitaka Ito, Kotaro Yoshioka, Shinki Tani, Kazuto Umezu, Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2022, 20, 2282-2292. (DOI: 10.1039/D1OB02482E)
Selective Utilization of Phosphorus Compounds by Chaetoceros Tenuissimus (Bacillariophyceae): Approach Using 31P Nuclear Magnetic Resonance Analysis
Haruo Yamaguchi, Masaki Zaima, Masao Adachi, Yuji Tomaru, Haruyasu Asahara and Nagatoshi Nishiwaki
Phycological Research 2022, 70, 151-159. (DOI: 10.1111/pre.12485)
Metal-Free and syn-Selective Hydrohalogenation of Alkynes through the Pseudo-Intramolecular Process
Haruyasu Asahara, Yusuke Mukaijo, Kengo Muragishi, Kento Iwai, Akitaka Ito and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2021, 5747-5755. (DOI: 10.1002/ejoc.202101134)
Selected as a Front Cover
Synthesis of Nitroaromatic Compounds via Three-Component Ring Transformations
Song Thi Le, Haruyasu Asahara and Nagatoshi Nishiwaki
Molecules 2021, 26, 639 (18 pages). (DOI: 10.3390/ molecules26030639 )
For special issue "25th Anniversary of Molecules—Recent Advances in Organic Synthesis"
One-Pot and Metal-Free Synthesis of 3-Arylated 4-Nitrophenols via Polyfunctionalized Cyclohexanones from β-Nitrostyrenes
Haruyasu Asahara, Minami Hiraishi, and Nagatoshi Nishiwaki
Beilstein Journal of Organic Chemistry, 2020, 16, 1830-1836. (DOI: 10.3762/bjoc.16.150)
Regiodivergent Ring Opening Reactions of 2-Arylated 3-Nitrocyclopropane-1,1-dicarboxylates Leading to Polyfunctionalized Dipoles
Haruyasu Asahara, Rikiya Kamidate, and Nagatoshi Nishiwaki
Heterocycles, 103, 379-391. (DOI: 10.3987/COM-20-S(K)21)
Dedicated to Professor Yasuyuki Kita on his 77th birthday
Vapochromic Properties of Diethenylpyrrole with Naphthyl Tethers Induced by Formation of Distorted Structure at the Solid State
Soichi Yokoyama, Haruyasu Asahara, and Nagatoshi Nishiwaki
Crystal Growth & Design 2020, 20, 1383-1387. (DOI: 10.1021/acs.cgd.9b01596)
Three Step Synthesis of Fully and Differently Arylated Pyridines
Mao Arita, Soichi Yokoyama, Haruyasu Asahara, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2020, 466-474. (DOI: 10.1002/ejoc.201901663)
Selected as a Noteworthy in ChemistryViews. Original Figure is Here.
Non-electronic Activation of Aromatic Ring by Simple Steric Repulsion between Substituents in 1-Methylquinolinium Salt Systems
Kento Iwai, Soichi Yokoyama, Haruyasu Asahara, and Nagatoshi Nishiwaki
Bulletin of the Chemical Society of Japan 2020, 93, 50-57. (DOI: 10.1246/bcsj.20190263)
Anion-Capture-Induced Fluorescence Enhancement of Bis(cyanostyryl)pyrrole Based on a Concept of Restricted Access to Conical Intersection
Soichi Yokoyama, Akitaka Ito, Haruyasu Asahara, and Nagatoshi Nishiwaki
Bulletin of the Chemical Society of Japan 2019, 92, 1807-1815. (DOI: 10.1246/bcsj.20190196)
Selected Paper
A Facile Synthesis of Oxiranes Possessing Three or Four Carbonyl Groups
Haruyasu Asahara, Shuhei Kikuchi, Yuto Unno, Soichi Yokoyama, Kotaro Yoshioka, Shinki Tani, Kazuto Umezu, and Nagatoshi Nishiwaki
Current Organic Chemistry 2019, 23, 97-102.(DOI: 10.2174/1385272823666190112103813)
Metal-Free O-Selective Direct Acylation of Amino Alcohols via Pseudo-Intramolecular Process
Soichi Yokoyama, Hiroshi Shibauchi, Haruyasu Asahara, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2019, 1125-1133.
Facile Synthesis of Onychines
Mao Arita, Soichi Yokoyama, Haruyasu Asahara, and Nagatoshi Nishiwaki
Synthesis 2019, 51, 2007-2013.(DOI: 10.1055/s-0037-1612058)
Alkynylation and Cyanation of Alkenes Using Diverse Properties of a Nitro Group
Haruyasu Asahara, Ayano Sofue, Yasuyuki Kuroda, and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 83, 13691-13699. (DOI: 10.1021/acs.joc.8b01865)
Unsymmetrical Tetra-acceptor-substituted Alkenes as Polyfunctionalized Building Blocks: A Divergent Synthesis of Densely Functionalized Pyrrolizines
Haruyasu Asahara, Shu Kawakami, Kotaro Yoshioka, Shinki Tani, Kazuto Umezu, and Nagatoshi Nishiwaki
Bulletin of the Chemical Society of Japan 2018, 91, 1715-1723.(DOI: 10.1246/bcsj.20180213)
This paper is dedicated to Mari
Phosphine Induced Dimerization of Propargyl Alcohols Leading to Allyl Propargyl Ethers
Kento Iwai, Soichi Yokoyama, Haruyasu Asahara and Nagatoshi Nishiwaki
Journal of Oleo Science 2018, 67, 773-778. (DOI: 10.5650/jos.ess17277)
Activation of 1-Methyl-5-nitro-2-pyrimidinone by Dearomatization Using a Secondary Amine
Haruyasu Asahara, Azusa Yasuoka and Nagatoshi Nishiwaki
Heterocycles 2018, 97, 253-259. (DOI: 10.3987/COM-17-S(T)14)
A Direct Synthesis of Trisubstituted Allenes from Propargyl Alcohols via Oxaphosphetane Intermediates
Kento Iwai, Soichi Yokoyama, Haruyasu Asahara and Nagatoshi Nishiwaki
Bulletin of the Chemical Society of Japan 2018, 91, 337-342. (DOI: 10.1246/bcsj.20170372)
Synthesis of Functionalized 4-Nitroanilines by Ring Transformation of Dinitropyridone with Enaminones
Saki Naito, Soichi Yokoyama, Haruyasu Asahara and Nagatoshi Nishiwaki
Tetrahedron Letters 2017, 58, 4699-4702. (DOI: 10.1016/j.tetlet.2017.11.003)
Direct Aziridination of Nitroalkenes Affording N-Alkyl-C-nitroaziridines and the Subsequent Lewis Acid Mediated Isomerization to β-Nitroenamines
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic Letters 2017, 19, 5442-5445. (DOI: 10.1021/acs.orglett.7b02724)
Synthesis of Functionalized 3-Cyanoisoxazoles Using a Dianionic Reagent
Kento Iwai, Haruyasu Asahara, and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 2017, 82, 5409-5415. (DOI: 10.1021/acs.joc.7b00811)
Hydrohalogenation of Ethynylpyridines Involving Nucleophilic Attack of a Halide Ion
Kengo Muragishi, Haruyasu Asahara, and Nagatoshi Nishiwaki
ACS Omega 2017, 2, 1265-1272. (DOI: 10.1021/acsomega.7b00133)
Tailor-made Synthesis of Fully Alkylated/Arylated Nicotinates by FeCl3-Mediated Condensation of Enamino Esters with Enones
Sho Hirai, Yurie Horikawa, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemical Communications 2017, 53, 2390-2393. (DOI: DOI:/10.1039/C7CC00051K)
Direct Amino-halogenation and Aziridination of the 2-Quinolone Framework by Sequential Treatment of 3-Nitro-2-quinolone with Amine and N-Halosuccinimide
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron 2017, 73, 1255-1264. (DOI: DOI:/10.1016/j.tet.2017.01.028)
Selected as a front cover of the issue.
Direct and Efficient Functionalization of the 1-Methyl-2-quinolone Framework
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Procedia Engineering 2017, 174, 1058-1066. (DOI: DOI:10.1016/j.proeng.2017.01.258)
Construction of Push-Pull Systems Using β-Formyl-β-nitroenamine
Yumi Nakaike, Haruyasu Asahara, and Nagatoshi Nishiwaki
Russian Chemical Bulletin, International Edition 2016, 65, 2129-2142. (Invited) (DOI: 10.1007/s11172-016-1561-2)
Investigation of a Green Oligomer of an Indolizine
Haruyasu Asahara, Ayaka Awane, Kengo Muragishi, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Arkivoc 2016, vi, 259-273. (DOI: 10.3998/ark.5550190.p009.93)
Acid Promoted Dimerization of α-Amino-α,β-unsaturated Amides Affording Bis(functionalized) Pyrrolinones
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Tetrahedron Letters 2016, 57, 5896-5898. (DOI: 10.1016/j.tetlet.2016.11.068)
Synthesis of 6-Substituted 2-Phenacylpyridines from 2-(Phenylethynyl)pyridine via Isoxazolo[2,3-a]pyridinium Salt
Song Thi Le, Toshiki Fujimoto, Haruyasu Asahara, and Nagatoshi Nishiwaki
Organic & Biomolecular Chemistry 2016, 14, 10674-10682. (DOI: 10.139/C6OB01942K)
Direct Synthesis of N-Acyl-N,O-hemiacetals via Nucleophilic Addition of Unactivated Amides and Their O-Acetylation: Access to α,α-Difunctionalized N-Acylimines
Haruyasu Asahara, Kanami Inoue, Shinki Tani, Kazuto Umezu, and Nagatoshi Nishiwaki
Advanced Synthesis & Catalysis 2016, 20, 2817-2828. (DOI: 10.1002/adsc.201600436)
Chemoselective Amination of β-Keto Amides
Sho Hirai, Haruyasu Asahara, and Nagatoshi Nishiwaki
Current Organic Chemistry 2016, 20, 2911-2916. (DOI: 10.2174/1385272820666160608101354)
Dual Behavior of Iodine Species in Condensation of Anilines and Vinyl Ethers Affording 2-Methylquinolines
Song Thi Le, Chisa Yasuoka, Haruyasu Asahara, and Nagatoshi Nishiwaki
Molecules 2016, 21, 827 (11 pages). (DOI: 10.3390/molecules21070827)
A Direct and Vicinal Functionalization of the 1-Methyl-2-quinolone Framework: 4-Alkoxylation and 3-Chlorination
Feiyue Hao, Haruyasu Asahara, and Nagatoshi Nishiwaki
Molecules 2016, 14, 5128-5135. (DOI: 10.139/C6OB00868B)
Construction of 3,5-Dinitrated 1,4-Dihydropyridines Modifiable at 1,4-Positions by a Reaction of β-Formyl-β-nitroenamines with Aldehydes
Haruyasu Asahara, Mai Hamada, Yumi Nakaike, and Nagatoshi Nishiwaki
RSC Advances 2015, 5, 90778-90784.
An Alternative Synthetic Approach to 3-Alkylated/Arylated 5-Nitropyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 2015, 80, 8856-8858.
Development of Variously Functionalized Nitrile Oxides
Haruyasu Asahara, Keita Arikiyo and Nagatoshi Nishiwaki
Beilstein Journal of Organic Chemistry 2015, 11, 1241-1245.
Functionalization of a Pyridine Framework via Intramolecular Reissert-Henze Reaction of N-Carbamoyloxypyridinium Salt aand Unexpected Insertion of Etherial Solvents
Haruyasu Asahara, Asuka Kataoka, Shotaro Hirao, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2015, 3994-3999.
Metal-free Synthesis of 2-Alkenyl/Alkynyl-5-nitropyridines Using a Three-component Ring Transformation
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Chemistry Letters 2015, 44, 776-778.
Synthesis of Diazabicyclo Compounds Possessing an α-Nitrolactam Framework
Haruyasu Asahara, Shota Takeda, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Tetrahedron Letters 2015, 56, 2504-2507.
Cyano-aci-nitroacetate as a Safe Cyano(nitro)methylation Reagent and its Synthetic Applications
Haruyasu Asahara and Nagatoshi Nishiwaki
Oleoscience 2015, 15, 165-172. (Invited)
Tailor-made Synthesis of N,N,2,6-Tetrasubstituted 4-Nitroanilines by Three-Component Ring Transformation of Dinitropyridone
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
European Journal of Organic Chemistry 2015, 1203-1206.
Development of a New Palladium Catalyst Supported on Phenolic Resin
Nagatoshi Nishiwaki, Sayaka Hamada, Tomoe Watanabe, Shotaro Hirao, Jun Sawayama, Haruyasu Asahara, Kazuhiko Saigo, Toru Kamata, and Masahiko Funabashi
RSC Advances 2015, 5, 4463-4467.
Metal-Free α-Hydroxylation of α-Unsubstituted β-Oxoesters and β-Oxoamides
Haruyasu Asahara and Nagatoshi Nishiwaki
The Journal of Organic Chemistry 2014, 79, 11735-11739.
An Effect of Microwave Irradiation on Pd/SiC Catalyst for Prolonging the Catalytic Life
Haruyasu Asahara, Yuki Kuribayashi, Pengyu Wang, Kazuya Kobiro, and Nagatoshi Nishiwaki
Current Microwave Chemistry 2014, 1, 142-147. (Invited)
Smart Decoration of Mesoporous TiO2 Nanospheres with Noble Metal Alloy Nanoparticles into Core-shell, Yolk-core-shell, and Surface Dispersion Morphologies
Pengyu Wang, Hiroko Tooriyama, Kazuya Yokoyama, Masataka, Ohtani, Haruyasu Asahara, Tomoya Konishi, Nagatoshi Nishiwaki, Masahiko Shimoda, Yoshiyuki Yamashita, Hideki Yoshikawa, and Kazuya Kobiro
European Journal of Inorganic Chemistry 2014, 4254-4257.
Revisiting Dimerization of Acetoacetamide Leading to 4,6-Dimethyl-2-pyridone-5-carboxamide
Sho Hirai, Haruyasu Asahara, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Journal of Oleo Science 2014, 63, 939-942.
Safe Cyano(nitro)methylating Reagent -Michael Addition of Cyano-aci-nitroacetate Leading to δ-Functionalized α-Nitronitriles-
Haruyasu Asahara, Kyo Muto, and Nagatoshi Nishiwaki
Tetrahedron 2014, 70, 6522-6528.
An Efficient Synthesis of Nitrated Cycloalka[b]pyridines
Song Thi Le, Haruyasu Asahara, and Nagatoshi Nishiwaki
Synthesis 2014, 46, 2175-2178.
Facilitation of the Reduction of Pd(II) by the Glass Surface -Development of a Glass-Supported Palladium Catalyst-
Nagatoshi Nishiwaki, Yasuyuki Mori, Erina Fukuoka, Haruyasu Asahara, Shotaro Hirao, Jun Sawayama, Kazuhiko Saigo, Tomoya Konishi, and Masahiko Shimoda
Chemical Physics Letters 2014, 608, 340-343.
Redox Chemistry of Nickel(II)-Complexes Supported by a Series of Non-innocent β-Diketiminate Ligands-
June Takaichi, Yuma Morimoto, Kei Ohkubo, Chizu Shimokawa, Takayuki Hojo, Seiji Mori, Haruyasu Asahara, Hideki Sugimoto, Nobutaka Fujieda, Nagatoshi Nishiwaki, Shunichi Fukuzumi, and Shinobu Itoh
Inorganic Chemistry 2014, 53, 6159-6169.
Synthesis of 2-Aryl-5-Nitropyridines by Three-Component Ring Transformation of 3,5-Dinitro-2-pyridone
Song Thi Le, Haruyasu Asahara, Kazuya Kobiro, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
Asian Journal of Organic Chemistry 2014, 3, 297-302.
An NMR Study on a Pseudo-Intramolecular Transacylation Reaction of an α-Aryl-β-keto Ester
Sho Hirai, Haruyasu Asahara, Shotaro Hirao, Jun Sawayama, Ryuichi Sugimoto, Kazuhiko Saigo, and Nagatoshi Nishiwaki
RSC Advances 2014, 4, 4889-4892.
Synthesis of Vicinally Functionalized 1,4-Dihydropyridines and Diazaheterocycles via a Pseudo-Intramolecular Process
Nagatoshi Nishiwaki, Shotaro Hirao, Jun Sawayama, Haruyasu Asahara, Ryuichi Sugimoto, Kazuya Kobiro, and Kazuhiko Saigo
Tetrahedron 2014, 70, 402-408.
Carbamoylnitrile Oxide and Inverse Electron-Demand 1,3-Dipolar Cycloaddition
Nagatoshi Nishiwaki and Haruyasu Asahara
in Methods and Applications of Cycloaddition Reactions in Organic Syntheses Chapter 9, pp 223-240, John Wiley & Sons, Hoboken, USA (2014).
Reactive 2-Quinolones Dearomatized by Steric Repulsion between 1-Methyl and 8-Substited Groups
Xin Chen, Kazuya Kobiro, Haruyasu Asahara, Kiyomi Kakiuchi, Ryuichi Sugimoto, Kazuhiko Saigo, Nagatoshi Nishiwaki
Tetrahedron 2013, 69, 4624−4630.
